Mayslake Peabody Estate is part of Mayslake Forest Preserve. The preserve, once home to Potawatomi Indians, encompasses 88 acres of natural resources. The rolling landscape includes 22 acres of wetlands, lakes, restored prairie, and two small oak savannas - one of the region's most endangered ecosystems. It is owned and operated by the Forest Preserve District of DuPage County and serves as one of its five education centers.

The mansion was built between 1919 and 1921 as the retirement home for Francis Stuyvesant Peabody, a coal baron and national figure in Democratic politics. The house was designed by renowned Chicago architect Benjamin H. Marshall. This venue hosts all kinds of events, including weddings. It is home to the First Folio Theatre company.